Abstract
Background: Diabetes mellitus (DM) is one of the non-communicable diseases that has become a major global
health concern due to its increasing prevalence. Suboptimal medication adherence often becomes a barrier to
successful therapy, which may lead to uncontrolled hyperglycemia and increase the risk of chronic
complications such as cardiovascular diseases, kidney disorders, and neuropathy.
Objective: The purpose of this study was To analyze the relationship between self-efficacy and family support
with medication adherence among patients with type 2 diabetes mellitus at Kedungwaru Public Health Center,
Tulungagung Regency.
Method: This study was a quantitative analytic observational study using a cross-sectional design with a
retrospective approach. The research was conducted at Kedungwaru Public Health Center, Tulungagung
Regency, East Java Province. The study population consisted of all patients with type 2 diabetes mellitus at
UPTD Kedungwaru Public Health Center, totaling 846 individuals. Based on the Slovin formula, the sample
size was determined to be 90 respondents. The sampling technique used was purposive sampling. Data were
analyzed using the chi-square test.
Results: The results showed that self-efficacy (p = 0.001; OR = 4.29) and family support (p = 0.001; OR =
4.29) were significantly associated with medication adherence among patients with type 2 diabetes mellitus at
Kedungwaru Public Health Center, Tulungagung Regency.
Conclusion: There is a significant relationship between self-efficacy and family support with medication
adherence among patients with type 2 diabetes mellitus. It is recommended to enhance the role of healthcare
providers in delivering continuous counseling and to develop family-based interventions to improve
medication adherence.

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